Welcome to HEFalMp, a functional map of the human genome! Functional
maps offer a way to interactively explore gene, pathway, process, and
disease associations predicted from integrating hundreds of publicly
available genomic datasets. You can focus on each entity - genes,
processes, or diseases - and examine functional associations predicted
from this data globally or in the context of a specific biological
process. Please note that HEFalMp does a great deal of calculation in
real time, so if you request a complicated analysis, it might take up to
a minute or two to complete.
Looking for inspiration? Try some of the sample queries listed below,
and you can click on any question mark popup
(?) or browse
through the Help linked from
the top of every page. You can always find out what specific
predictions or data generated a score by clicking on it, right down to
the values for a single gene pair in a particular experiment. Feel
free to contact us with any
questions, comments, or suggestions, and thanks for your interest!
If you're interested in finding new genes that might be
associated with Alzheimer's, you can investigate a
disease as it relates to all genes in the context
of protein processing (or learning and/or memory)
and request Alzheimer disease.
Similarly, you can get a list of genes predicted to function in
autophagy by focusing on a biological process as it
relates to all genes in the context of autophagy,
and investigate the specific process of autophagy.
To predict what function(s) the gene ALOX5AP might have,
investigate a gene to see how it relates to
biological processes in the context of all biological
processes, and ask for the specific gene
alox5ap.
To see what other genes ALOX5AP might relate to in a
particular biological process, investigate a gene to see
how it relates to all genes in the context of
chemotaxis, and ask for the specific gene
alox5ap.
Want to see the entire portion of the predicted functional
relationship network around ALOX5AP and its partners
in chemotaxis? Try querying a set of genes as they
relate to all genes in the context of chemotaxis,
and ask for the genes alox5ap alox5 fcer1g itgb2.
If you use HEFalMp or functional maps in your research, please cite
our publication:
